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Levofloxacin may also be used to treat people who have been exposed to anthrax or certain types of plague. The use of Levaquin at 500 mg orally or intravenously once a day is helpful when given for a period of 28 days. Levoquin 500 MG Tablet is an antibiotic medicine that contains Levofloxacin. For treatment, antiprotozoal drugs are used, such as Metronidazole, Tinidazole or antibacterial drugs - Monomycin, oxytetracycline, ampicillin. Levaquin may also be used for purposes not listed in this medication guide. Levaquin is used in the treatment of bacterial infection; bladder infection; anthrax; anthrax prophylaxis; plague and belongs to the drug class quinolones It is an antibiotic used for the treatment of certain bacterial infections. It is an antibiotic used for the treatment of certain bacterial infections. 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